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Gene Regulation and Therapeutics for Cancer


1st Edition 

by Surinder K. Batra (Editor), Moorthy Palanimuthu Ponnusamy (Editor) 

Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.


Year: 2021
Pages: 329
Language: English
Format: PDF
Size: 14 MB
Publisher: CRC Press
ISBN-10: 1138712426
ISBN-13: 978-1138712423
Tag: Download Book Gene Regulation and Therapeutics for Cancer